Dr.Elvira Hermawati was born in Indonesia (Manado) and graduated in 2009 as an undergraduate student from the Institut Teknologi Bandung (ITB) in the department of chemistry, where she explored the isolation of natural substances from Desmodium triquetrum. After performing research in conjunction with Meiji Pharmacetical University (2010) under the supervision of Prof. Lia Dewi Juliawaty, she resumed her studies in the same place for a Master degree (2011) on the isolation of secondary metabolites from Garcinia mangostana as an anticancer. She graduated in 2017 as a doctoral student after continuing her studies on the isolation of secondary metabolites from the endophytic fungi Xylaria, Phomopsis, and Talaromyces wortmanii under the supervision of Prof. Dr. Euis Holisotan.
Together with Professor Dr. Yana M. Syah (Alm.) and Dr. Ade Danova, we are working on the isolation of secondary metabolites from plants, as well as the synthesis and transformation of secondary metabolites and the production of FDA-approved anticancer derivatives. They are also working on a number of laboratory bioactivity assays, including tyrosine kinase, betalactamase, caspase-3, and caspase-7, as well as antibacterial. She is presently a lecturer in organic chemistry at the Institut Teknologi Bandung, Department of Chemistry, as well as the manager of the NMR Laboratory and the leader of the integrated chemistry laboratory, Faculty of Mathematics and Natural Sciences, ITB, Indonesia.

Research Grants: 

• Anggota Peneliti (2024): Hibah Penelitian “Pengembangan Metode Produksi Bahan Obat (Active Pharmaceutical Ingredient) dari Bahan Baku Terbarukan (BioAPI” didanai oleh program PRIME SteP ADB-ITB.
• Ketua Peneliti (2024): Penelitian Kompetitif Nasional (PPS-PTM) dengan judul “Sintesis dan Uji Mekanisme Penghambatan Piperidinium Bis-Lawsone sebagai Kandidat Obat Antidiabetes Tipe 2” didanai oleh Kemdikbudristek.
• Anggota Peneliti (2024): Hibah Joint Research dengan Peneliti Luar Negeri PPMI FMIPA Institut Teknologi Bandung dengan judul “Sintesis dan Uji Inhibisi Sulfonamidacalkon terhadap Enzim EGFR Tirosin Kinase sebagai Kandidat Antikanker Paru-Paru”.
• Anggota Peneliti (2024): Hibah Penelitian PPMI KK Kimia Organik FMIPA Institut Teknologi Bandung dengan judul “Sintesis dan Uji Inhibisi Senyawa Turunan Timol terhadap Enzim α-Glukosidase sebagai Obat Antidiabetes Tipe II”.

International Publication: 

1. Agustini, D. M., Hermawati, E., Giri-Rachman, E. A., Happyana, N., & Juliawaty, L. D. (2024). Synthesis and Biological Activity Evaluation of Two Derivatives of 7-Aminocephalosporanic Acid. Chemistry Africa, 1-9.
2. Mujahidin, D., Noviany, I., Hermawati, E., Danova, A., Heliawati, L., & Syah, Y.M. (2024). Isolation and Inhibition Study of Eryvarin D and E from the Root Barks of Eryhtrina veriegata against receptor tyrosine kinases. Rasayan Journal of Chemistry, 17(3), 832-837.
3. Nugraheni, D., Hermawati, E., Helmanto, H., Firmansyah, D., Syah, Y. M., & Juliawaty, L. D. (2024). A Pyrone and Flavonoid Derivatives from Cryptocarya crassinervia and their Inhibitory Properties against Receptor Tyrosine Kinases. Journal of Mathematical & Fundamental Sciences, 55(3).
4. Kurniadewi, F., Aqilah, A. S., Kartika, I. R., Nurjayadi, M., Hermawati, E., & Danova, A. (2024). Garciniaxanthone E and 12b-Hydroxy-des-D-garcigerrin A from The Tree Bark Garcinia dulcis and their Inhibitory Properties against Receptor Tyrosine Kinases. Jurnal Kimia Valensi, 10(1), 20-26.
5. Happyana, N., Hermawati, E., Ellita, S. D., Juliawaty, L. D., Syah, Y. M., & Hakim, E. H. (2024). Procaine treatment altered metabolite profiles of endophytic fungus Talaromyces wortmannii collected from Morus cathayana Hemsl. Phytochemistry Letters, 60, 249-256.
6. Danova, A., Pattanapanyasat, K., Hengphasatporn, K., Shigeta, Y., Rungrotmongkol, T., Hermawati, E., & Chavasiri, W.(2024). Unlocking E-arylidene Steroid Derivatives as Promising α-Glucosidase Inhibitors. Chemistry Select, 9(9), e202303887.
7. Naufal, M., Hermawati, E., Syah, Y. M., Hidayat, A. T., Hidayat, I. W., & Al-Anshori, J. (2024). Structure–Activity Relationship Study and Design Strategies of Hydantoin, Thiazolidinedione, and Rhodanine-Based Kinase Inhibitors: A Two-Decade Review. ACS omega, 9(4), 4186-4209.
8. Purnamasari, Y., Hermawati, E., Mujahidin, D., Happyana, N., & Syah, Y. M. (2024). Xanthorrhizol derivatives and their biological properties as caspase-7 inhibitors. Natural Product Research, 1-9.
9. Rachmadhaningtiyas, D. A., Hermawati, E., Juliawaty, L. D., & Wahyuningrum, D. (2023). Direct Synthesis of 8‐Fluorocaffeine and Its Transformation to 8‐Substituted Caffeine. ChemistrySelect, 8(47), e202303074.
10. Agustini, D. M., Hermawati, E., Mujahidah, N. N., & Riga, R. (2023). Coumarin Derivatives from Hydrangea macrophylla and Evaluation of Their Cytotoxic Activity. Chemistry Africa, 6(4), 1747-1751.

Patent: 

1. Proses Pembuatan Obat Jantung Bisoprolol Melalui Prekursor 4-((2-Isopropoksietoksi)Metil)Fenol. No. P00202312605 (Pemeriksaan Formalitas oleh DJKI 2023).
2. Metode Pemurnian Senyawa 6-Fluoro-3-Hidroksipirazin-2-Karboksamida Sebagai Obat Antivirus Rna. No. P00202307068 (Pemeriksaan Formalitas oleh DJKI 2023).

Contact Me Here:

E-mail: elvira.hermawati@itb.ac.id

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